Ukungena okuqhubekayo komnqobi waseSpain uDon Nuño Beltrán de Guzmán ebheke emazweni asentshonalanga yezwe, ukuze kwandiswe ukubusa namandla akhe kulezo zindawo, kwaholela ekusungulweni kwesifundazwe esisha esibizwa ngokuthi yi-Kingdom of New Galicia.
Lesi sifunda sasihlala amaqembu ahlukahlukene omdabu, ahlala ecekela phansi izindawo abaseSpain ababesungula kuso. Umphathi wamaphoyisa kaNuño de Guzmán, uKaputeni Juan B. de Oñate uthole imiyalo yokuthula lezo zifundazwe futhi athole iVilla de Guadalajara endaweni ebizwa ngeNochistlán, iqiniso alifeza ngoJanuwari 5, 1532. Ngenxa yokuhlaselwa komdabu kaningi kuleli dolobha kwadingeka athuthe unyaka kamuva aye eTonalá futhi kamuva aye eTlacotlán. Ukudluliswa kwesithathu kwenziwa ukulungisa idolobha elise-Atemajac Valley, lapho idolobha lasungulwa khona ngoFebhuwari 14, 1542 lapho kwakukhona khona uCristóbal de Oñate njengombusi waseNew Galicia noDon Antonio de Mendoza, owayeyinduna yaseNew Spain, oqoke imeya kaMiguel de Ibarra kanye nombusi wesikhundla.
Idolobha lakhula ngokushesha futhi laqala ukuqhudelana nelaseCompostela (namuhla eyiTepic), ngaleso sikhathi okwakuyisihlalo semibuso yezenkolo neyomphakathi, ukuze izakhamizi zaseGuadalajara zicindezele iziphathimandla ze-Audiencia, inkosi UFelipe II uthathe isinqumo sokukhipha iSitifiketi sangomhlaka-10 Meyi 1560 ukuthi asuke eCompostela aye eGuadalajara, eKhathedrali, eRoyal Court kanye naseziphathimandla zikaMgcinimafa.
Isakhiwo sasemadolobheni sasihlelwe ngokuya ngamanye amadolobha amakoloni, ngakho-ke ukwakheka kwawo kwakwenziwa ngesimo se-chessboard kusuka kulokho okwakuyisikwele iSan Fernando. Kamuva izindawo zaseMexicaltzingo nase-Analco zasungulwa nguFray Antonio de Segovia, kanye nomakhelwane waseMezquitán, okungenye yezindala kunazo zonke. Izindlu zehholo ledolobha nazo zakhiwa, zibhekene nethempeli lamanje laseSan Agustín kanye nesonto lokuqala lesifunda lapho kutholakala khona iPalace of Justice.
Namuhla, idolobha elihle kakhulu, elinezakhiwo eziningi zamakoloni, likhombisa izibonelo eziningi zokwakha, njengeCathedral yalo, indawo okumele ibonwe, eyakhiwe phakathi kuka-1561 no-1618 ngumdwebi uMartín Casillas. Isitayela sakhe sihlukaniswe njengebaroque engenayo. Isakhiwo saso esiqinile sikhuphuka phambi kwePlaza de Guadalajara yanamuhla, nemibhoshongo yayo enelukuluku lokuthi, yize ingeyona yesitayela sokuqala sesakhiwo, njengamanje yaziwa njengophawu lwenhlokodolobha yaseGuadalajara. Imibhoshongo yakudala yabhujiswa ngekhulu leshumi nesishiyagalolunye ngokuzamazama komhlaba, ngakho-ke leyo enayo namuhla ingeziwe. Ingaphakathi lethempeli li-semi-Gothic ngesitayela, kufaka phakathi ama-vault alo enziwe ngentambo.
Eminye imingcele yezenkolo yekhulu le-16 yisigodlo seSan Francisco, esasungulwa ngo-1542 eduze komfula, endaweni yase-Analco, futhi sabhujiswa ngokuphelele kuNguquko. Ithempeli lalo, elilungiswe kabusha ekupheleni kwekhulu le-17, kanye nolwaseBaroque olungolayini abanesizotha bakaSolomon, liyagcinwa. Isigodlo seSan Agustín, sasungulwa ngonyaka we-1573 yiRoyal Ordinance kaFelipe II futhi njengamanje sigcina ithempeli laso elinemigqa emikhulu yaseHerrerian nengaphakathi laso elinamagobongo.
ISanta María de Gracia, esinye sezisekelo zesonto, kwakuhlala izindela zaseDominican zasePuebla, ezakhiwa ngo-1590 phambi kwePlaza de San Agustín futhi zakhokhelwa nguHernán Gómez de la Peña. Ukwakhiwa kwahlala ngamabhulokhi ayisithupha, yize namuhla kuqhubeka kuphela ithempeli lawo, eline-neoclassical facade kusukela engxenyeni yesibili yekhulu le-18.
